Abnormal Cervical Cells
 
  » What are abnormal cervical cells?
» What causes abnormal cervical cells?
» How are abnormal cervical cells detected?
» How are Pap test results reported?
» Are there additional tests for women diagnosed with abnormal cervical cells?
» Can abnormal cervical cells be treated?
 
  What are abnormal cervical cells?

Abnormal cervical cells are cells in the lining of the cervix that have changed in appearance. This is also called cervical dysplasia. The more severe the cervical abnormality, the more likely it is that cervical cancer could develop in the future. Most often the development of cervical cancer from abnormal cervical cell changes can take a number of years. However, in rare cases, it has developed within a year.

 
What causes abnormal cervical cells?

Abnormal cervical cells may have a number of different causes (such as an infection or inflammation) but are commonly caused by certain types of human papillomavirus (HPV). There are about 30 types of HPV that affect the genital area, and these are known as genital HPV. Some types can cause abnormal cells in the lining of the cervix to turn into cancer. Other types can cause genital warts and other benign (abnormal but noncancerous) changes in the cervix.

Other consequences
of HPV include
Abnormal
Cervical
Cells


All types of genital HPV can lead to abnormal Pap tests—that's why gynecological exams are so important. So, be sure to get a Pap test as often as your healthcare professional recommends.

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  How are abnormal cervical cells detected?

The primary way to detect abnormal cervical cells is through a Pap test. A Pap test (also known as a Papanicolaou smear) is part of a gynecological exam. It helps detect abnormal cervical cells before they have a chance to become precancer or cervical cancer. The results of a Pap test can help healthcare professionals decide if further testing or treatments are necessary.
  How are Pap test results reported?

While most healthcare professionals may simply say that the results of the Pap test are normal or abnormal, some may use acronyms such as ASCUS, LSIL, or HSIL.

ASCUS stands for atypical squamous cells of undetermined significance. A diagnosis of ASCUS means that the abnormalities seen in cervical cells are mild and their nature is uncertain.

LSIL stands for low-grade squamous intraepithelial lesion and means that there are more definite but still mildly abnormal cervical cells.

HSIL, or high-grade squamous intraepithelial lesion, means there are severely abnormal cervical cells that have a high likelihood of progressing to cervical cancer.

  Are there additional tests for women diagnosed with abnormal cervical cells?

If the results of a Pap test indicate that you have abnormal cervical cells, it's important to follow your healthcare professional's recommendations for more testing, such as repeat Pap testing, HPV DNA testing, a colposcopy, and possible biopsy.

An abnormal biopsy result may be reported as CIN or cervical intraepithelial neoplasia. Neoplasia means an abnormal growth of cells. Intraepithelial refers to the layer of cells that forms the surface of the cervix. The term CIN, along with a number (1 to 3), describes how much of the thickness of the lining of the cervix contains abnormal cells. A diagnosis of CIN 3 means there are severely abnormal cervical cells throughout the entire thickness of the lining of the cervix.

Most abnormal cells in the lining of the cervix will eventually go away because an immune response from the body occurs on its own. If the abnormalities are mild, the healthcare professional may choose to closely monitor them. However, if the abnormalities are more severe, removing these cells can almost always prevent cervical cancer from developing in the future.

  Can abnormal cervical cells be treated?

Methods commonly used to treat abnormal cervical cells include cryosurgery (freezing that destroys abnormal cervical cells), LEEP (loop electrosurgical excision procedure, the removal of abnormal cervical cells using a hot wire loop), and conventional surgery.

The healthcare professional may request an additional follow-up examination to make sure that the abnormal cells do not come back. If the abnormal cells reappear, the treatment can be repeated.

  Abnormal cervical cells can be the first consequence of HPV. So an abnormal Pap test is an important warning sign that shouldn't be ignored. Find out more about human papillomavirus (HPV) and its connection to cervical cancer, genital warts, and other consequences in the other sections of this site. Talk to your healthcare professional to learn more about these topics.
  This site is intended for residents of The Philippines.